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Using two separate drugs to shed weight can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight loss and the those who go through it you need to err assisting caution and permit the FDA do its job and demand some investigation be done so your public is aware of the side effects and dangers of the medications before we bring them. Keep in mind that drug companies are in business to generate income and that they would say anything to keep people on his or her medications. Researchers found that participants using this drug for a year, dropped excess weight within 4 weeks and have kept the load off during the entire 56 weeks from the study. Contrave is a combination of the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which can be made up of many active ingredient, that might make them more potent and safer. Combo-pilling could be the newest fad or even better the newest ahead under scrutiny and therefore it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular may be the fact that as of right now there are not any long term prescription weight loss supplements that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be approved by the FDA. Seizures can be a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug also can raise blood pressure and heartrate, and must not be used in people with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must not used in patients with uncontrolled high blood pressure level, in addition to by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients which has a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients to the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. --Participating in support groups that really help the family in the addict recover (for example Al-Anon or Nar-Anon).